What is the chance that Jane and Peter’s next child will have CF?
Cystic fibrosis is an autosomal recessive disease.
2/3 (risk of being a carrier) x 1/25 (carrier risk for Caucasian) x 1/4 (both carriers and then have an affected child) = 1/ 150
Chance that Jane and Peter’s next child will have CF is 1/150.
