Risk calculation - autosomal recessive condition (Cystic Fibrosis)

Jane and Peter have two healthy children but Jane’s sister has a child recently diagnosed with CF. Peter has no family history of CF. What is the chance that Jane and Peter’s next child will have CF? Both of them are of Caucasian ancestry.

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John Kristoffer Sacro
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John Kristoffer Sacro
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Angelu Gabrielle Castro
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Angelu Gabrielle Castro
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