Activity 1

CHAN, Patricia Lee A.

CHAN, Patricia Lee A.

by Patricia Lee Chan -
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  1. Trauma or injury in the area will trigger the release of signaling chemicals like histamine to alert the body that there is an issue. The redness and warmth associated with inflammation are the dilation of blood vessels near the injured to facilitate increased blood flow to the infected area. Increased permeability allows for immune cell migration where WBC (neutrophils and macrophages) are able exit the blood stream to reach the damaged tissue to neutralize and remove any foreign substances, such as bacteria or debris. The body initiates tissue repair mechanisms so that once the threat is neutralized, anti-inflammatory signals help resolve the inflammation, and the healing process begins.
  2. Innate immunity provides immediate protection against pathogens. It’s rapid and generalized defense is crucial in the early stages of an infection before the adaptive immune system with its specific response takes over. It’s mechanisms include physical barriers (skin prevents pathogens from entering the body), chemical defenses (stomach acid destroy bacteria and parasites), phagocytosis (identifying and engulfing bacteria), and interferons (inhibit the replication of viruses) in response to viral infections.