You do not consume alcoholic beverages, but your friend does, and he consumes these drinks regularly and in large amounts, If we could examine your liver cells and compare with your friend, would we see a difference in smooth ER and peroxisomes?
One of the functions of the smooth ER is to help detoxify lipid-soluble molecules or harmful substances like alcohol in the liver while peroxisomes oxidize alcohol. If we compare the smooth ER and peroxisomes of a human who does not drink alcoholic beverages and an alcoholic person, the latter would have more smooth ER and peroxisomes present in their liver cells.