You do not consume alcoholic beverages, but your friend does, and he consumes these drinks regularly and in large amounts, If we could examine your liver cells and compare with your friend, would we see a difference in smooth ER and peroxisomes?
Yes. Smooth endoplasmic reticulum and peroxisomes both perform chemical detoxification. A person who consumes alcoholic beverages will have more smooth er and peroxisomes. Furthermore, excessive alcohol consumption induces pathological stress responses such as endoplasmic reticulum (ER) stress response. ER stress is a condition in which misfolded proteins accumulate in the endoplasmic reticulum causing alcoholic disorders of the major organs such as the liver, pancreas, heart, and brain.