You do not consume alcoholic beverages, but your friend does, and he consumes these drinks regularly and in large amounts, If we could examine your liver cells and compare with your friend, would we see a difference in smooth ER and peroxisomes?
Peroxisomes are in charge of detoxifying alcohol and other harmful compounds. On the other hand, the smooth ER synthesizes lipids, phospholipids, etc. They work together to help the alcoholic friend break down the harmful chemicals that are in the alcohol. As a result, he has a larger number of peroxisomes and smooth ER due to his excessive intake of alcoholic drinks.