You do not consume alcoholic beverages, but your friend does, and he consumes these drinks regularly and in large amounts. If we could examine your liver cells and compare with your friend, would we see a difference in smooth ER and peroxisomes?
When my friend’s liver cells are compared to mine, there would be a difference in the smooth endoplasmic reticulum and peroxisomes. Consumption of too much alcohol causes a pathological stress response due to the accumulation of unfolded proteins in the endoplasmic reticulum. This phenomenon includes risks of alcoholic diseases in the body’s vital organs such as the liver, pancreas, brain, and heart. Additionally, people with excessive alcohol consumption tend to have increased or larger peroxisomes compared to non-alcohol drinkers, and peroxisomal abnormalities may also lead to lethal human diseases. With all of these mentioned, an examination of the liver cells of mine and my friend’s would show the negative effects of too much alcohol in my friend’s liver while mine is still functioning healthily and effectively, without any signs of infections.