You do not consume alcoholic beverages, but your friend does, and he consumes these drinks regularly and in large amounts. If we could examine your liver cells and compare with your friend, would we see a difference in smooth ER and peroxisomes?
The smooth endoplasmic reticulum and the peroxisomes are both essential for the body to combat the negative effects of chemicals consumed. Drugs, chemicals, acids, and other forms of toxic substances are oxidized by the peroxisome and detoxified by the smooth endoplasmic reticulum, which lessens the effects of the consumed toxic substances.
In order for the body to protect itself from the danger caused by the chemicals, it responds in a way that there will be an increase in the number of smooth ER and peroxisomes. The number of the organelles differ in each person according to the level of alcohols induced in the body. The increase in the number of both organelles is necessary to maintain balance and to prevent the body from catching diseases.