TANILON, Pauline Joy B.
Activity 2: Parts of the Cell
You do not consume alcoholic beverages, but your friend does, and he consumes these drinks regularly and in large amounts, If we could examine your liver cells and compare with your friend, would we see a difference in smooth ER and peroxisomes?
Yes, there would be a difference between my liver cells and those of my friend in terms of the smooth ER and peroxisomes. Drugs and other chemicals are oxidized by peroxisomes and detoxified by the smooth ER, respectively. Undoubtedly, there would be variations in these structures as alcohol intake is increased.
In my friend's situation, the liver cells will have more smooth ER and peroxisomes, showing that the liver cells have produced more smooth ER and peroxisomes in order to process the elevated levels of toxins brought on by the alcohol.
Furthermore, drinking too much alcohol causes a variety of pathogenic stress reactions, including the endoplasmic reticulum (ER) stress response. Major organ problems caused by alcoholism include those of the liver, pancreas, heart, and brain. ER stress, a state in which unfolded or misfolded protein accumulates in the ER, plays a role in these disorders.
References:
Ji, C. (2012). Mechanisms of Alcohol-Induced Endoplasmic Reticulum Stress and Organ Injuries. Biochemistry Research International, 2012, 1–12. https://doi.org/10.1155/2012/216450
KHANDOKER_AKTER. (2022). Cells and Their Organelles. Quizlet. https://quizlet.com/463958426/cells-and-their-organelles-flash-cards/