Day 3 Module D: Neuromuscular Blocking Agents
Section outline
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Neuromuscular blocking agents (NMBAs) produce muscle relaxation either by directly depolarizing acetylcholine (ACh) receptors or competing with ACh for the recognition sites to prevent normal receptor function.
At the end of this module, the clinical clerk should be able to:
- Discuss the physiology and pharmacology of neuromuscular blocking agents.
- Differentiate between non-depolarizing and depolarizing neuromuscular block agents.
- Describe monitoring neuromuscular blockade.
- Discuss reversal for neuromuscular blockade.
- Select the appropriate neuromuscular blocking and reversal agents for clinical use.
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For a more comprehensive understanding of the topic, it is recommended to read the following chapter on your reference book:
Weigel WA, et al. (2023). Neuromuscular blocking drugs. In Cullen BF, et al (Eds). Barash, Cullen and Stoelting's Clinical Anesthesia. (9th ed., pp 505-529). Wolters Kluwer.
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In this video, we learn more about three neuromuscular blocking agents, succinylcholine, atracurium, and rocuronium.
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Test Yourself: Neuromuscular Blocking Agents Quiz
After completing the activities for this module, try the following quiz on neuromuscular blocking agents. You are allowed two attempts to complete this quiz. Ten (10) minutes will be allotted for each attempt. Remember to submit you responses in order for them to be recorded.
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Please post your questions here. Posted questions can be answered by staff and other students. Be sure that your question relates to the materials in this module.
You can read through other questions and post a response, or ask a question of your own. But remember, please limit your questions and responses to 100 words or less.
If you have a question about specific content (videos or quiz questions) please be specific in your questions! If members of the faculty can't find the video or question, they will not be able to answer your question.